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Structure paper

TitleA single ligand is sufficient to activate EGFR dimers.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 10861-10866, Year 2012
Publish dateOct 14, 2011 (structure data deposition date)
AuthorsLiu, P. / Cleveland, T.E. / Bouyain, S. / Byrne, P.O. / Longo, P.A. / Leahy, D.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:22699492
MethodsX-ray diffraction
Resolution3.03 Å
Structure data

PDB-3u7u:
Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta
Method: X-RAY DIFFRACTION / Resolution: 3.03 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE REGULATOR / signaling protein / TRANSFERASE-TRANSFERASE REGULATOR COMPLEX / Glycosylation

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