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TitleStructural basis of potent and broad HIV-1 fusion inhibitor CP32M
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 26618-26629, Year 2012
Publish dateAug 22, 2011 (structure data deposition date)
AuthorsYao, X. / Chong, H. / Zhang, C. / Qiu, Z. / Qin, B. / Han, R. / Waltersperger, S. / Wang, M.T. / He, Y. / Cui, S.
External linksJ. Biol. Chem. / PubMed:22679024
MethodsX-ray diffraction
Resolution2.019 - 2.034 Å
Structure data

PDB-3vgy:
Structure of HIV-1 gp41 NHR/fusion inhibitor complex P321
Method: X-RAY DIFFRACTION / Resolution: 2.034 Å

PDB-3vh7:
Structure of HIV-1 gp41 NHR/fusion inhibitor complex P21
Method: X-RAY DIFFRACTION / Resolution: 2.019 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • human immunodeficiency virus type 1
KeywordsMEMBRANE PROTEIN/INHIBITOR / 6-helix bundle / membrane fusion inhibition / MEMBRANE PROTEIN-INHIBITOR complex

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