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-Structure paper
Title | Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 109, Page 9959-9964, Year 2012 |
Publish date | Nov 18, 2011 (structure data deposition date) |
![]() | Ostrov, D.A. / Grant, B.J. / Pompeu, Y.A. / Sidney, J. / Harndahl, M. / Southwood, S. / Oseroff, C. / Lu, S. / Jakoncic, J. / de Oliveira, C.A. ...Ostrov, D.A. / Grant, B.J. / Pompeu, Y.A. / Sidney, J. / Harndahl, M. / Southwood, S. / Oseroff, C. / Lu, S. / Jakoncic, J. / de Oliveira, C.A. / Yang, L. / Mei, H. / Shi, L. / Shabanowitz, J. / English, A.M. / Wriston, A. / Lucas, A. / Phillips, E. / Mallal, S. / Grey, H.M. / Sette, A. / Hunt, D.F. / Buus, S. / Peters, B. |
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Methods | X-ray diffraction |
Resolution | 1.999 Å |
Structure data | ![]() PDB-3upr: |
Chemicals | ![]() ChemComp-1KX: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM / HLA-B*57:01 / MHC / antigen presenting cell / T-cell receptor / human leukocyte antigen / drug hypersensitivity / abacavir hypersensitivity / repertoire-altering small molecule / immune response / Immunoglobulin-like beta-sandwich |