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TitlePresence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.
Journal, issue, pagesProtein Sci., Vol. 21, Page 1103-1112, Year 2012
Publish dateJan 24, 2012 (structure data deposition date)
AuthorsSalameh, M.A. / Soares, A.S. / Alloy, A. / Radisky, E.S.
External linksProtein Sci. / PubMed:22610453
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-4dg4:
Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI)
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • bos taurus (domestic cattle)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Human mesotrypsin / canonical inhibitor / BPTI / HYDROLASE-HYDROLASE INHIBITOR complex

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