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TitleCrystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants
Journal, issue, pagesFebs Lett., Vol. 586, Page 1715-1718, Year 2012
Publish dateMar 30, 2012 (structure data deposition date)
AuthorsMuraoka, S. / Shima, F. / Araki, M. / Inoue, T. / Yoshimoto, A. / Ijiri, Y. / Seki, N. / Tamura, A. / Kumasaka, T. / Yamamoto, M. / Kataoka, T.
External linksFebs Lett. / PubMed:22584058
MethodsX-ray diffraction
Resolution1.9 - 2.3 Å
Structure data

PDB-4efl:
Crystal structure of H-Ras WT in complex with GppNHp (state 1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4efm:
Crystal structure of H-Ras G12V in complex with GppNHp (state 1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4efn:
Crystal structure of H-Ras Q61L in complex with GppNHp (state 1)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Rossmann Fold / GTPase / GTP-binding

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