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TitleStructural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
Journal, issue, pagesScience, Vol. 336, Page 728-732, Year 2012
Publish dateFeb 16, 2012 (structure data deposition date)
AuthorsLangelier, M.F. / Planck, J.L. / Roy, S. / Pascal, J.M.
External linksScience / PubMed:22582261
MethodsX-ray diffraction
Resolution3.25 Å
Structure data

PDB-4dqy:
Structure of Human PARP-1 bound to a DNA double strand break
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA / PARP / poly(ADP-ribose) polymerase / DNA binding protein / adp-ribosyl transferase / PARP-like zinc finger / poly(adp-ribosyl)ation / DNA damage detection / TRANSFERASE-DNA complex

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