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TitleDomain organization differences explain Bcr-Abl's preference for CrkL over CrkII.
Journal, issue, pagesNat. Chem. Biol., Vol. 8, Page 590-596, Year 2012
Publish dateMar 9, 2012 (structure data deposition date)
AuthorsJankowski, W. / Saleh, T. / Pai, M.T. / Sriram, G. / Birge, R.B. / Kalodimos, C.G.
External linksNat. Chem. Biol. / PubMed:22581121
MethodsNMR (solution)
Structure data

PDB-2lqn:
Solution structure of CRKL
Method: SOLUTION NMR

PDB-2lqw:
Solution structure of phosphorylated CRKL
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / SH2 / SH3 / v-crk sarcoma virus CT10 oncogene homolog (avian)-like / v-crk sarcoma virus CT10 / oncogene homolog / (avian)-like / pCRKL

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