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TitleHuman Prorenin Structure Sheds Light on a Novel Mechanism of Its Autoinhibition and on Its Non-Proteolytic Activation by the (Pro)renin Receptor.
Journal, issue, pagesJ. Mol. Biol., Vol. 421, Page 100-111, Year 2012
Publish dateJan 4, 2012 (structure data deposition date)
AuthorsMorales, R. / Watier, Y. / Bocskei, Z.
External linksJ. Mol. Biol. / PubMed:22575890
MethodsX-ray diffraction
Resolution2.93 Å
Structure data

PDB-3vcm:
Crystal structure of human prorenin
Method: X-RAY DIFFRACTION / Resolution: 2.93 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / aspartic proteases / prorenin receptor

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