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TitleStructural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 20823-20829, Year 2012
Publish dateApr 12, 2012 (structure data deposition date)
AuthorsStieglitz, B. / Haire, L.F. / Dikic, I. / Rittinger, K.
External linksJ. Biol. Chem. / PubMed:22549881
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-4emo:
Crystal structure of the PH domain of SHARPIN
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Pleckstrin homology (PH) domain / LUBAC / SIPL1 / linear ubiquitin / HOIL-1L / HOIP

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