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-Structure paper
Title | Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2 |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 109, Page 7421-7426, Year 2012 |
Publish date | Mar 17, 2012 (structure data deposition date) |
Authors | Ohto, U. / Fukase, K. / Miyake, K. / Shimizu, T. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:22532668 |
Methods | X-ray diffraction |
Resolution | 2.48 - 2.7 Å |
Structure data | PDB-3vq1: PDB-3vq2: |
Chemicals | ChemComp-NAG: ChemComp-LP4: ChemComp-LP5: ChemComp-HOH: ChemComp-DAO: ChemComp-MYR: |
Source |
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Keywords | IMMUNE SYSTEM / Leucine rich repeat MD-2 related lipid recognition / receptor innate immunity / lipid binding / glycosylation / secreted |