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Structure paper

TitleRationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface
Journal, issue, pagesPlos One, Vol. 7, Page e33340-e33340, Year 2012
Publish dateFeb 16, 2011 (structure data deposition date)
AuthorsYu, C.M. / Peng, H.P. / Chen, I.C. / Lee, Y.C. / Chen, J.B. / Tsai, K.C. / Chen, C.T. / Chang, J.Y. / Yang, E.W. / Hsu, P.C. ...Yu, C.M. / Peng, H.P. / Chen, I.C. / Lee, Y.C. / Chen, J.B. / Tsai, K.C. / Chen, C.T. / Chang, J.Y. / Yang, E.W. / Hsu, P.C. / Jian, J.W. / Hsu, H.J. / Chang, H.J. / Hsu, W.L. / Huang, K.F. / Ma, A.C. / Yang, A.S.
External linksPlos One / PubMed:22457753
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-3auv:
Predicting Amino Acid Preferences in the Complementarity Determining Regions of an Antibody-Antigen Recognition Interface
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / sc-dsFv (disulfide-stabilized scFv) / scFv / monovalent antibody / VEGF / antibody engineering

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