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Structure paper

Title1,3-1,4-alpha-L-fucosynthase that specifically introduces Lewis a/x antigens into type-1/2 chains
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 16709-16719, Year 2012
Publish dateOct 31, 2011 (structure data deposition date)
AuthorsSakurama, H. / Fushinobu, S. / Hidaka, M. / Yoshida, E. / Honda, Y. / Ashida, H. / Kitaoka, M. / Kumagai, H. / Yamamoto, K. / Katayama, T.
External linksJ. Biol. Chem. / PubMed:22451675
MethodsX-ray diffraction
Resolution1.6 - 2.1 Å
Structure data

PDB-3ues:
Crystal structure of alpha-1,3/4-fucosidase from Bifidobacterium longum subsp. infantis complexed with deoxyfuconojirimycin
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-3uet:
Crystal structure of alpha-1,3/4-fucosidase from Bifidobacterium longum subsp. infantis D172A/E217A mutant complexed with lacto-N-fucopentaose II
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-DFU:
(2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • bifidobacterium longum subsp. infantis (bacteria)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Tim Barrel / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE

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