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Structure paper

TitleMatrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 15935-15946, Year 2012
Publish dateDec 23, 2011 (structure data deposition date)
AuthorsBatra, J. / Robinson, J. / Soares, A.S. / Fields, A.P. / Radisky, D.C. / Radisky, E.S.
External linksJ. Biol. Chem. / PubMed:22427646
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3v96:
Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR/HYDROLASE / Metzincin / OB-fold / Metalloproteinase / Protease inhibitor / HYDROLASE INHIBITOR-HYDROLASE complex

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