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-Structure paper
| タイトル | Structural insights into the classification of Mud Crab Reovirus. |
|---|---|
| ジャーナル・号・ページ | Virus Res, Vol. 166, Issue 1-2, Page 116-120, Year 2012 |
| 掲載日 | 2012年3月6日 |
著者 | Zengwei Huang / Xiexiong Deng / Yinyin Li / Hongjun Su / Kunpeng Li / Zhixun Guo / Peirui Zheng / Haidong Xu / Jianguo He / Qinfen Zhang / Shaoping Weng / ![]() |
| PubMed 要旨 | Cryo-electron microscopy was applied to analyze mud crab reovirus (MCRV), which causes 'sleeping disease' in mud crab, Scylla serrata, a marine species cultured in China. We present here the three ...Cryo-electron microscopy was applied to analyze mud crab reovirus (MCRV), which causes 'sleeping disease' in mud crab, Scylla serrata, a marine species cultured in China. We present here the three dimensional structure of MCRV at 13.8Å resolution. The outer capsid shell is composed of 260 trimers with complete T=13 icosahedral symmetry. A major difference between MCRV and previously reported aquareoviruses is that it lacks a pentameric turret structure. These results together with recently published molecular biological evidence (Deng et al., 2012) indicate that, from a structural perspective, MCRV should be classified as a new member of the family Reoviridae. |
リンク | Virus Res / PubMed:22421382 |
| 手法 | EM (単粒子) |
| 解像度 | 13.8 Å |
| 構造データ | ![]() EMDB-2054: |
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