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TitleStructural insights into the classification of Mud Crab Reovirus.
Journal, issue, pagesVirus Res, Vol. 166, Issue 1-2, Page 116-120, Year 2012
Publish dateMar 6, 2012
AuthorsZengwei Huang / Xiexiong Deng / Yinyin Li / Hongjun Su / Kunpeng Li / Zhixun Guo / Peirui Zheng / Haidong Xu / Jianguo He / Qinfen Zhang / Shaoping Weng /
PubMed AbstractCryo-electron microscopy was applied to analyze mud crab reovirus (MCRV), which causes 'sleeping disease' in mud crab, Scylla serrata, a marine species cultured in China. We present here the three ...Cryo-electron microscopy was applied to analyze mud crab reovirus (MCRV), which causes 'sleeping disease' in mud crab, Scylla serrata, a marine species cultured in China. We present here the three dimensional structure of MCRV at 13.8Å resolution. The outer capsid shell is composed of 260 trimers with complete T=13 icosahedral symmetry. A major difference between MCRV and previously reported aquareoviruses is that it lacks a pentameric turret structure. These results together with recently published molecular biological evidence (Deng et al., 2012) indicate that, from a structural perspective, MCRV should be classified as a new member of the family Reoviridae.
External linksVirus Res / PubMed:22421382
MethodsEM (single particle)
Resolution13.8 Å
Structure data

EMDB-2054:
Electron cryo-microscopy of Mud Crab Reovirus
Method: EM (single particle) / Resolution: 13.8 Å

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