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Structure paper

TitleMode of peroxisome proliferator-activated receptor gamma activation by luteolin.
Journal, issue, pagesMol. Pharmacol., Vol. 81, Page 788-799, Year 2012
Publish dateJul 18, 2011 (structure data deposition date)
AuthorsPuhl, A.C. / Bernardes, A. / Silveira, R.L. / Yuan, J. / Campos, J.L. / Saidemberg, D.M. / Palma, M.S. / Cvoro, A. / Ayers, S.D. / Webb, P. ...Puhl, A.C. / Bernardes, A. / Silveira, R.L. / Yuan, J. / Campos, J.L. / Saidemberg, D.M. / Palma, M.S. / Cvoro, A. / Ayers, S.D. / Webb, P. / Reinach, P.S. / Skaf, M.S. / Polikarpov, I.
External linksMol. Pharmacol. / PubMed:22391103
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-3sz1:
Human PPAR gamma ligand binding domain in complex with luteolin and myristic acid
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-KNA:
nonanoic acid

ChemComp-LU2:
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one

ChemComp-MYR:
MYRISTIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPAR GAMMA / NUCLEAR RECEPTOR / LUTEOLIN

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