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TitleThe ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold
Journal, issue, pagesPlos Pathog., Vol. 8, Page e1002550-e1002550, Year 2012
Publish dateJan 12, 2012 (structure data deposition date)
AuthorsZhang, A.P.P. / Bornholdt, Z.A. / Liu, T. / Abelson, D.M. / Lee, D.E. / Li, S. / Woods Jr., V.L. / Saphire, E.O.
External linksPlos Pathog. / PubMed:22383882
MethodsX-ray diffraction
Resolution2 - 2.1 Å
Structure data

PDB-3vne:
Structure of the ebolavirus protein VP24 from Sudan
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3vnf:
Structure of the ebolavirus protein VP24 from Sudan
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4d9o:
Structure of ebolavirus protein VP24 from Reston
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • sudan ebolavirus
  • reston ebolavirus
KeywordsVIRAL PROTEIN / ebolavirus / interferon antagonist / VP24 / STAT1 / Zaire / Sudan / Reston / VP35 / karyopherin alpha / IFN response pathway

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