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TitleStructural basis of TLR5-flagellin recognition and signaling.
Journal, issue, pagesScience, Vol. 335, Page 859-864, Year 2012
Publish dateDec 14, 2011 (structure data deposition date)
AuthorsYoon, S.I. / Kurnasov, O. / Natarajan, V. / Hong, M. / Gudkov, A.V. / Osterman, A.L. / Wilson, I.A.
External linksScience / PubMed:22344444
MethodsX-ray diffraction
Resolution2.47 - 2.83 Å
Structure data

PDB-3v44:
Crystal structure of the N-terminal fragment of zebrafish TLR5
Method: X-RAY DIFFRACTION / Resolution: 2.83 Å

PDB-3v47:
Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin
Method: X-RAY DIFFRACTION / Resolution: 2.47 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • danio rerio (zebrafish)
  • eptatretus burgeri (inshore hagfish)
  • salmonella enterica subsp. enterica serovar dublin (bacteria)
KeywordsIMMUNE SYSTEM / flagellin / innate immunity / Leucine-rich repeat / innate immune receptor

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