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TitleStructure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation.
Journal, issue, pagesScience, Vol. 335, Page 709-712, Year 2012
Publish dateJan 12, 2012 (structure data deposition date)
AuthorsSong, J. / Teplova, M. / Ishibe-Murakami, S. / Patel, D.J.
External linksScience / PubMed:22323818
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-4da4:
Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-ZN:
Unknown entry

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTransferase/DNA / Maintenance DNA methylation / Covalent Complex / Transferase-DNA complex

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