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TitleMDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA.
Journal, issue, pagesEmbo J., Vol. 31, Page 1714-1726, Year 2012
Publish dateSep 12, 2011 (structure data deposition date)
AuthorsBerke, I.C. / Modis, Y.
External linksEmbo J. / PubMed:22314235
MethodsX-ray diffraction
Resolution2.003 Å
Structure data

PDB-3ts9:
Crystal Structure of the MDA5 Helicase Insert Domain
Method: X-RAY DIFFRACTION / Resolution: 2.003 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsANTIVIRAL PROTEIN / HYDROLASE / helix bundle / FANCM helicase / Super Family 2 helicase / SF2 helicase / DExD/H helicase / Rig-I-like helicase

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