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Structure paper

TitleRequirements for efficient correction of DeltaF508 CFTR revealed by analyses of evolved sequences
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 148, Page 164-174, Year 2012
Publish dateJun 17, 2011 (structure data deposition date)
AuthorsMendoza, J.L. / Schmidt, A. / Li, Q. / Nuvaga, E. / Barrett, T. / Bridges, R.J. / Feranchak, A.P. / Brautigam, C.A. / Thomas, P.J.
External linksCell(Cambridge,Mass. ) / PubMed:22265409
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-3si7:
The crystal structure of the NBD1 domain of the mouse CFTR protein, deltaF508 mutant
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / cystic fibrosis / ATP-binding domain

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