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-Structure paper
Title | Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 55, Page 1698-1705, Year 2012 |
Publish date | Jan 17, 2012 (structure data deposition date) |
![]() | Bryan, M.C. / Whittington, D.A. / Doherty, E.M. / Falsey, J.R. / Cheng, A.C. / Emkey, R. / Brake, R.L. / Lewis, R.T. |
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Methods | X-ray diffraction |
Resolution | 2.03 Å |
Structure data | ![]() PDB-4dce: |
Chemicals | ![]() ChemComp-0JF: ![]() ChemComp-HOH: |
Source |
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![]() | Transferase/Inhibitor / receptor tyrosine kinase / inhibitor / NPM-ALK / EML4-ALK / Transferase-Inhibitor complex |