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TitleAn amino acid position at crossroads of evolution of protein function: antibiotic sensor domain of BlaR1 protein from Staphylococcus aureus versus clasS D beta-lactamases
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 8232-8241, Year 2012
Publish dateDec 5, 2011 (structure data deposition date)
AuthorsKumarasiri, M. / Llarrull, L.I. / Borbulevych, O. / Fishovitz, J. / Lastochkin, E. / Baker, B.M. / Mobashery, S.
External linksJ. Biol. Chem. / PubMed:22262858
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-3uy6:
BlaR1 sensor domain from Staphylococcus aureus with N439V mutation
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
Keywordspenicillin-binding protein / ANTIBIOTIC SENSOR PROTEIN

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