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TitleThe crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor.
Journal, issue, pagesJ. Biol. Chem., Year 2012
Publish dateAug 18, 2011 (structure data deposition date)
AuthorsHamming, O.J. / Kang, L. / Svensson, A. / Karlsen, J.L. / Rahbek-Nielsen, H. / Paludan, S.R. / Hjorth, S.A. / Bondensgaard, K. / Hartmann, R.
External linksJ. Biol. Chem. / PubMed:22235133
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3tgx:
IL-21:IL21R complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-NI:
NICKEL (II) ION

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsCYTOKINE/CYTOKINE RECEPTOR / Class I cytokine / Class I cytokine Receptor / sugarbridge / Fibronectin domain / Signaling / CYTOKINE-CYTOKINE RECEPTOR complex

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