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Structure paper

TitleStructure Guided Understanding of NAD(+) Recognition in Bacterial DNA Ligases.
Journal, issue, pagesAcs Chem. Biol., Vol. 7, Page 571-580, Year 2012
Publish dateNov 19, 2011 (structure data deposition date)
AuthorsLahiri, S.D. / Gu, R.F. / Gao, N. / Karantzeni, I. / Walkup, G.K. / Mills, S.D.
External linksAcs Chem. Biol. / PubMed:22230472
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-3uq8:
Structure of adenylation domain of Haemophilus influenzae DNA ligases bound to NAD+ in adenylated state.
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-HOH:
WATER

Source
  • haemophilus influenzae (bacteria)
KeywordsLIGASE / Adenylated protein / ATP-grasp / Rossmann fold / Adenylation

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