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Structure paper

TitleHuman tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
Journal, issue, pagesJ. Mol. Biol., Vol. 416, Page 467-485, Year 2012
Publish dateJul 21, 2011 (structure data deposition date)
AuthorsVendeix, F.A. / Murphy, F.V. / Cantara, W.A. / Leszczynska, G. / Gustilo, E.M. / Sproat, B. / Malkiewicz, A. / Agris, P.F.
External linksJ. Mol. Biol. / PubMed:22227389
MethodsX-ray diffraction
Resolution2.8 - 3.11 Å
Structure data

PDB-3t1h:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.11 Å

PDB-3t1y:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PAR:
PAROMOMYCIN / medication*YM

ChemComp-ZN:
Unknown entry

Source
  • thermus thermophilus (bacteria)
KeywordsRibosome/Antibiotic / Protein Synthesis / tRNA / Ribosome-Antibiotic complex

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