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Structure paper

TitleStabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 119-, Year 2012
Publish dateOct 17, 2011 (structure data deposition date)
AuthorsDeupi, X. / Edwards, P. / Singhal, A. / Nickle, B. / Oprian, D. / Schertler, G. / Standfuss, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:22198838
MethodsX-ray diffraction
Resolution3.3 Å
Structure data

PDB-4a4m:
Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-RET:
RETINAL

ChemComp-ACT:
ACETATE ION

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-PLM:
PALMITIC ACID

ChemComp-HOH:
WATER

Source
  • bos taurus (cattle)
KeywordsSIGNALING PROTEIN / G-PROTEIN / G-PROTEIN-COUPLED RECEPTORS / SIGNAL TANSDUCTION / VISUAL SYSTEM / METARHODOPSIN-II

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