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TitleAntibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential.
Journal, issue, pagesNAT. MED. (N. Y. ), Vol. 18, Page 143-147, Year 2012
Publish dateNov 27, 2011 (structure data deposition date)
AuthorsSela-Passwell, N. / Kikkeri, R. / Dym, O. / Rozenberg, H. / Margalit, R. / Arad-Yellin, R. / Eisenstein, M. / Brenner, O. / Shoham, T. / Danon, T. ...Sela-Passwell, N. / Kikkeri, R. / Dym, O. / Rozenberg, H. / Margalit, R. / Arad-Yellin, R. / Eisenstein, M. / Brenner, O. / Shoham, T. / Danon, T. / Shanzer, A. / Sagi, I.
External linksNAT. MED. (N. Y. ) / PubMed:22198278
MethodsX-ray diffraction
Resolution2.18 Å
Structure data

PDB-3utz:
Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Structural Genomics / Israel Structural Proteomics Center / ISPC / Fab domain

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