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-Structure paper
Title | Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 56, Page 1240-1246, Year 2012 |
Publish date | Oct 3, 2011 (structure data deposition date) |
![]() | Eakin, A.E. / Green, O. / Hales, N. / Walkup, G.K. / Bist, S. / Singh, A. / Mullen, G. / Bryant, J. / Embrey, K. / Gao, N. ...Eakin, A.E. / Green, O. / Hales, N. / Walkup, G.K. / Bist, S. / Singh, A. / Mullen, G. / Bryant, J. / Embrey, K. / Gao, N. / Breeze, A. / Timms, D. / Andrews, B. / Uria-Nickelsen, M. / Demeritt, J. / Loch, J.T. / Hull, K. / Blodgett, A. / Illingworth, R.N. / Prince, B. / Boriack-Sjodin, P.A. / Hauck, S. / Macpherson, L.J. / Ni, H. / Sherer, B. |
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Methods | X-ray diffraction |
Resolution | 1.64 - 1.85 Å |
Structure data | ![]() PDB-3u2d: ![]() PDB-3u2k: |
Chemicals | ![]() ChemComp-08B: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-087: |
Source |
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![]() | ISOMERASE/ISOMERASE INHIBITOR / protein-inhibitor complex / ATP-binding / structure-based drug design / antimicrobial / ISOMERASE-ISOMERASE INHIBITOR complex |