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| Title | Potent inhibitors of LpxC for the treatment of Gram-negative infections. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 55, Page 914-923, Year 2012 |
| Publish date | Sep 30, 2011 (structure data deposition date) |
 Authors | Brown, M.F. / Reilly, U. / Abramite, J.A. / Arcari, J.T. / Oliver, R. / Barham, R.A. / Che, Y. / Chen, J.M. / Collantes, E.M. / Chung, S.W. ...Brown, M.F. / Reilly, U. / Abramite, J.A. / Arcari, J.T. / Oliver, R. / Barham, R.A. / Che, Y. / Chen, J.M. / Collantes, E.M. / Chung, S.W. / Desbonnet, C. / Doty, J. / Doroski, M. / Engtrakul, J.J. / Harris, T.M. / Huband, M. / Knafels, J.D. / Leach, K.L. / Liu, S. / Marfat, A. / Marra, A. / McElroy, E. / Melnick, M. / Menard, C.A. / Montgomery, J.I. / Mullins, L. / Noe, M.C. / O'Donnell, J. / Penzien, J. / Plummer, M.S. / Price, L.M. / Shanmugasundaram, V. / Thoma, C. / Uccello, D.P. / Warmus, J.S. / Wishka, D.G. |
 External links | J. Med. Chem. / PubMed:22175825 |
| Methods | X-ray diffraction |
| Resolution | 2 Å |
| Structure data |  PDB-3u1y: |
| Chemicals |  ChemComp-ZN:  ChemComp-03I:  ChemComp-HOH: |
| Source |
|
 Keywords | Hydrolase/Hydrolase inhibitor / Pseudomonas aeruginosa / lpxc / gram negative / Hydrolase-Hydrolase inhibitor complex |
pseudomonas aeruginosa (bacteria)