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TitleDesign, synthesis, evaluation, and structure of vitamin D analogues with furan side chains.
Journal, issue, pagesChemistry, Vol. 18, Page 603-612, Year 2012
Publish dateAug 26, 2011 (structure data deposition date)
AuthorsFraga, R. / Zacconi, F. / Sussman, F. / Ordonez-Moran, P. / Munoz, A. / Huet, T. / Molnar, F. / Moras, D. / Rochel, N. / Maestro, M. / Mourino, A.
External linksChemistry / PubMed:22162241
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-3tkc:
Design, Synthesis, Evaluation and Structure of Vitamin D Analogues with Furan Side Chains
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-FMV:
(1S,3R,5Z,7E,14beta,17alpha,20S)-20-[5-(1-hydroxy-1-methylethyl)furan-2-yl]-9,10-secopregna-5,7,10-triene-1,3-diol

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / alpha-helical sandwich / calcitriol / phosphorylation / nucleus

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