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Structure paper

TitleStructural insights into the autoactivation mechanism of p21-activated protein kinase
Journal, issue, pagesStructure, Vol. 19, Page 1752-1761, Year 2011
Publish dateDec 26, 2010 (structure data deposition date)
AuthorsWang, J. / Wu, J.-W. / Wang, Z.-X.
External linksStructure / PubMed:22153498
MethodsX-ray diffraction
Resolution1.801 - 2.09 Å
Structure data

PDB-3q4z:
Structure of unphosphorylated PAK1 kinase domain
Method: X-RAY DIFFRACTION / Resolution: 1.887 Å

PDB-3q52:
Structure of phosphorylated PAK1 kinase domain
Method: X-RAY DIFFRACTION / Resolution: 1.801 Å

PDB-3q53:
Structure of phosphorylated PAK1 kinase domain in complex with ATP
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase domain / signalling pathway

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