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Structure paper

TitleMolecular determinants of magnolol targeting both RXR(alpha) and PPAR(gamma).
Journal, issue, pagesPlos One, Vol. 6, Page e28253-e28253, Year 2011
Publish dateMar 18, 2011 (structure data deposition date)
AuthorsZhang, H. / Xu, X. / Chen, L. / Chen, J. / Hu, L. / Jiang, H. / Shen, X.
External linksPlos One / PubMed:22140563
MethodsX-ray diffraction
Resolution2 - 2.8 Å
Structure data

PDB-3r5m:
Crystal structure of RXRalphaLBD complexed with the agonist magnolol
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3r5n:
Crystal structure of PPARgammaLBD complexed with the agonist magnolol
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MLO:
5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/TRANSCRIPTION AGONIST / nuclear receptor / transcription factor / TRANSCRIPTION-TRANSCRIPTION AGONIST complex

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