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Structure paper

TitleStructural insights into the neutralization mechanism of a higher primate antibody against dengue virus.
Journal, issue, pagesEmbo J., Vol. 31, Page 767-779, Year 2012
Publish dateOct 21, 2011 (structure data deposition date)
AuthorsCockburn, J.J. / Navarro Sanchez, M.E. / Goncalvez, A.P. / Zaitseva, E. / Stura, E.A. / Kikuti, C.M. / Duquerroy, S. / Dussart, P. / Chernomordik, L.V. / Lai, C.J. / Rey, F.A.
External linksEmbo J. / PubMed:22139356
MethodsX-ray diffraction
Resolution2.71 - 3.232 Å
Structure data

PDB-3uaj:
Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2
Method: X-RAY DIFFRACTION / Resolution: 3.232 Å

PDB-3uc0:
Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • dengue virus 4
  • pan troglodytes (chimpanzee)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / dengue antibody membrane fusion / VIRAL PROTEIN-IMMUNE SYSTEM complex

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