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-Structure paper
Title | Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 20, Page 1878-1886, Year 2012 |
Publish date | Oct 11, 2011 (structure data deposition date) |
Authors | Filippakopoulos, P. / Picaud, S. / Fedorov, O. / Keller, M. / Wrobel, M. / Morgenstern, O. / Bracher, F. / Knapp, S. |
External links | Bioorg. Med. Chem. / PubMed:22137933 |
Methods | X-ray diffraction |
Resolution | 1.39 - 1.8 Å |
Structure data | PDB-3u5j: PDB-3u5k: PDB-3u5l: |
Chemicals | ChemComp-08H: ChemComp-EDO: ChemComp-HOH: ChemComp-08J: ChemComp-08K: |
Source |
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Keywords | SIGNALING PROTEIN/INHIBITOR / Bromodomain-containing protein 4 isoform long / BRD4 / Bromodomain containing protein 4 / CAP / HUNK1 / MCAP / Mitotic chromosome associated protein / Structural Genomics Consortium / SGC / SIGNALING PROTEIN-INHIBITOR complex |