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-Structure paper
Title | Novel and selective spiroindoline-based inhibitors of sky kinase. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 22, Page 190-193, Year 2012 |
Publish date | Feb 24, 2011 (structure data deposition date) |
![]() | Powell, N.A. / Kohrt, J.T. / Filipski, K.J. / Kaufman, M. / Sheehan, D. / Edmunds, J.E. / Delaney, A. / Wang, Y. / Bourbonais, F. / Lee, D.Y. ...Powell, N.A. / Kohrt, J.T. / Filipski, K.J. / Kaufman, M. / Sheehan, D. / Edmunds, J.E. / Delaney, A. / Wang, Y. / Bourbonais, F. / Lee, D.Y. / Schwende, F. / Sun, F. / McConnell, P. / Catana, C. / Chen, H. / Ohren, J. / Perrin, L.A. |
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Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-3qup: |
Chemicals | ![]() ChemComp-LUN: ![]() ChemComp-HOH: |
Source |
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![]() | Transferase/transferase inhibitor / protein kinase inhibitor / receptor tyrosine kinase / spirocycle / Kinase domain / Phosphotransfer / Gas6 ligand / Cytoplasmic surface / Transferase-transferase inhibitor complex |