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TitleStructural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 1269-1278, Year 2012
Publish dateOct 25, 2011 (structure data deposition date)
AuthorsYu, E.D. / Girardi, E. / Wang, J. / Mac, T.T. / Yu, K.O. / Van Calenbergh, S. / Porcelli, S.A. / Zajonc, D.M.
External linksJ. Biol. Chem. / PubMed:22110136
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-3ubx:
Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-09N:
(11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Immunology / mouse CD1d/NKT / mAb

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