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Structure paper

TitleStable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
Journal, issue, pagesJ. Immunol., Vol. 187, Page 6393-6401, Year 2011
Publish dateDec 21, 2010 (structure data deposition date)
AuthorsMahalingam, B. / Ajroud, K. / Alonso, J.L. / Anand, S. / Adair, B.D. / Horenstein, A.L. / Malavasi, F. / Xiong, J.P. / Arnaout, M.A.
External linksJ. Immunol. / PubMed:22095715
MethodsX-ray diffraction
Resolution2.7 - 3 Å
Structure data

PDB-3q3g:
Crystal Structure of A-domain in complex with antibody
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-3qa3:
Crystal Structure of A-domain in complex with antibody
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM/CELL ADHESION / IMMUNE SYSTEM-CELL ADHESION COMPLEX / IMMUNE SYSTEM/ cell adhesion / IMMUNE SYSTEM- cell adhesion complex

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