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TitleConformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 108, Page 19329-19334, Year 2011
Publish dateMar 1, 2011 (structure data deposition date)
AuthorsPainter, C.A. / Negroni, M.P. / Kellersberger, K.A. / Zavala-Ruiz, Z. / Evans, J.E. / Stern, L.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:22084083
MethodsX-ray diffraction
Resolution2.302 - 2.712 Å
Structure data

PDB-3qxa:
HLA-DR1 bound with CLIP peptide
Method: X-RAY DIFFRACTION / Resolution: 2.712 Å

PDB-3qxd:
F54C HLA-DR1 bound with CLIP peptide
Method: X-RAY DIFFRACTION / Resolution: 2.302 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MHC class II

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