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TitleInsights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 108, Page 18672-18677, Year 2011
Publish dateSep 21, 2011 (structure data deposition date)
AuthorsWu, X. / Bradley, M.J. / Cai, Y. / Kummel, D. / De La Cruz, E.M. / Barr, F.A. / Reinisch, K.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:22065758
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-3tw8:
GEF domain of DENND 1B in complex with Rab GTPase Rab35
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / longin domain / Rab GTPase / guanine exchange factor

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