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Structure paper

TitleCrystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 2130-2143, Year 2012
Publish dateAug 19, 2011 (structure data deposition date)
AuthorsPastore, C. / Topalidou, I. / Forouhar, F. / Yan, A.C. / Levy, M. / Hunt, J.F.
External linksJ. Biol. Chem. / PubMed:22065580
MethodsX-ray diffraction
Resolution3.01 - 3.2 Å
Structure data

PDB-3thp:
Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-3tht:
Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / Structural Genomics / PSI-Biology / Northeast Structural Genomics Consortium / NESG / alpha-beta two domain-protein containing a zinc structure motif / tRNA modifying enzyme / Alpha-beta two domain protein containing a zinc structure motif

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