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TitleBacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNA(Phe) with 3,4-Dihydroxy-L-Phenylalanine.
Journal, issue, pagesChem. Biol., Vol. 18, Page 1221-1229, Year 2011
Publish dateAug 14, 2011 (structure data deposition date)
AuthorsMoor, N. / Klipcan, L. / Safro, M.G.
External linksChem. Biol. / PubMed:22035791
MethodsX-ray diffraction
Resolution2.2044 - 2.8524 Å
Structure data

PDB-3teg:
Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNAPhe with 3,4-Dihydroxy-L-Phenylalanine (L-Dopa)
Method: X-RAY DIFFRACTION / Resolution: 2.2044 Å

PDB-3teh:
Crystal structure of Thermus thermophilus Phenylalanyl-tRNA synthetase complexed with L-dopa
Method: X-RAY DIFFRACTION / Resolution: 2.8524 Å

Chemicals

ChemComp-DAH:
3,4-DIHYDROXYPHENYLALANINE / neurotransmitter*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • thermus thermophilus (bacteria)
KeywordsLIGASE / dopa / L-dopa / tRNA / aaRS

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