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Structure paper

TitleThe miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.
Journal, issue, pagesBiochemistry, Vol. 50, Page 10350-10358, Year 2011
Publish dateAug 3, 2011 (structure data deposition date)
AuthorsZahn, K.E. / Averill, A. / Wallace, S.S. / Doublie, S.
External linksBiochemistry / PubMed:22026756
MethodsX-ray diffraction
Resolution2.71 - 3 Å
Structure data

PDB-3tab:
5-hydroxycytosine paired with dGMP in RB69 gp43
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3tae:
5-hydroxycytosine paired with dAMP in RB69 gp43
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-3taf:
5-fluorocytosine paired with ddGMP in RB69 gp43
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3tag:
5-fluorocytosine paired with dAMP in RB69 gp43
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • enterobacteria phage rb69 (virus)
  • escherichia phage rb69 (virus)
  • synthetic construct (others)
KeywordsTransferase/DNA / Transferase-DNA complex

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