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-Structure paper
Title | Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases |
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Journal, issue, pages | Chemmedchem, Vol. 6, Page 1971-1976, Year 2011 |
Publish date | Oct 25, 2009 (structure data deposition date) |
![]() | Gumpena, R. / Kishor, C. / Ganji, R.J. / Addlagatta, A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.45 - 2.3 Å |
Structure data | ![]() PDB-3ked: ![]() PDB-3puu: ![]() PDB-3qjx: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-DAB: ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-MLA: ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() ChemComp-SER: ![]() ChemComp-MLI: |
Source |
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![]() | HYDROLASE / aminopeptidase / thermolysin like active site / amino switch / inhibitor / ligand design / Cell inner membrane / Cell membrane / Membrane / Metal-binding / Metalloprotease / Protease / mutant / thermolysin / zinc binding / peptidase / Thermolysin like catalytic domain / L-Serine complex |