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-Structure paper
Title | A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. |
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Journal, issue, pages | Cancer Cell, Vol. 20, Page 472-486, Year 2011 |
Publish date | Sep 29, 2010 (structure data deposition date) |
![]() | Schaefer, G. / Haber, L. / Crocker, L.M. / Shia, S. / Shao, L. / Dowbenko, D. / Totpal, K. / Wong, A. / Lee, C.V. / Stawicki, S. ...Schaefer, G. / Haber, L. / Crocker, L.M. / Shia, S. / Shao, L. / Dowbenko, D. / Totpal, K. / Wong, A. / Lee, C.V. / Stawicki, S. / Clark, R. / Fields, C. / Lewis Phillips, G.D. / Prell, R.A. / Danilenko, D.M. / Franke, Y. / Stephan, J.P. / Hwang, J. / Wu, Y. / Bostrom, J. / Sliwkowski, M.X. / Fuh, G. / Eigenbrot, C. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 3.7 Å |
Structure data | ![]() PDB-3p0v: ![]() PDB-3p0y: ![]() PDB-3p11: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-HOH: ![]() ChemComp-GOL: ![]() ChemComp-NAG: |
Source |
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![]() | IMMUNE SYSTEM / beta-sandwich / antigens EGFR and HER3 / antigens EGFR / antigens HER3 |