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Structure paper

TitleStructural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Journal, issue, pagesGenes Dev., Vol. 25, Page 2266-2277, Year 2011
Publish dateMar 7, 2011 (structure data deposition date)
AuthorsSengoku, T. / Yokoyama, S.
External linksGenes Dev. / PubMed:22002947
MethodsX-ray diffraction
Resolution1.803 - 1.85 Å
Structure data

PDB-3avr:
Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II)
Method: X-RAY DIFFRACTION / Resolution: 1.803 Å

PDB-3avs:
Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II)
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-OGA:
N-OXALYLGLYCINE / inhibitor*YM

ChemComp-ZN:
Unknown entry

ChemComp-NI:
NICKEL (II) ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/STRUCTURAL PROTEIN / Cupin superfamily / tri/dimethyllysine demethylase / OXIDOREDUCTASE-STRUCTURAL PROTEIN complex / OXIDOREDUCTASE

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