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Structure paper

TitleStructural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6.
Journal, issue, pagesDev. Cell, Vol. 21, Page 862-873, Year 2011
Publish dateMay 16, 2011 (structure data deposition date)
AuthorsAhn, V.E. / Chu, M.L. / Choi, H.J. / Tran, D. / Abo, A. / Weis, W.I.
External linksDev. Cell / PubMed:22000856
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3s2k:
Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / wnt co-receptor / beta-propeller / EGF domain / wnt signaling / wnt inhibitor / glycosylation

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