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| Title | Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 54, Page 8099-8109, Year 2011 |
| Publish date | Oct 12, 2011 (structure data deposition date) |
Authors | LaMarche, M.J. / Leeds, J.A. / Amaral, K. / Brewer, J.T. / Bushell, S.M. / Dewhurst, J.M. / Dzink-Fox, J. / Gangl, E. / Goldovitz, J. / Jain, A. ...LaMarche, M.J. / Leeds, J.A. / Amaral, K. / Brewer, J.T. / Bushell, S.M. / Dewhurst, J.M. / Dzink-Fox, J. / Gangl, E. / Goldovitz, J. / Jain, A. / Mullin, S. / Neckermann, G. / Osborne, C. / Palestrant, D. / Patane, M.A. / Rann, E.M. / Sachdeva, M. / Shao, J. / Tiamfook, S. / Whitehead, L. / Yu, D. |
External links | J. Med. Chem. / PubMed:21999529 |
| Methods | X-ray diffraction |
| Resolution | 2.12 - 2.45 Å |
| Structure data | ![]() PDB-3u6b: ![]() PDB-3u6k: |
| Chemicals | ![]() ChemComp-MG: ![]() ChemComp-GDP: ![]() ChemComp-HOH: |
| Source |
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Keywords | translation factor/antibiotic / translation factor-antibiotic complex |
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