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Structure paper

TitleStructural basis for distinct binding properties of the human galectins to thomsen-friedenreich antigen
Journal, issue, pagesPlos One, Vol. 6, Page e25007-e25007, Year 2011
Publish dateMay 4, 2011 (structure data deposition date)
AuthorsBian, C.F. / Zhang, Y. / Sun, H. / Li, D.F. / Wang, D.C.
External linksPlos One / PubMed:21949831
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-3aya:
Crystal structure of galectin-3 CRD domian complexed with Thomsen-Friedenreich antigen
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3ayc:
Crystal structure of galectin-3 CRD domian complexed with GM1 pentasaccharide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3ayd:
Crystal structure of galectin-3 CRD domian complexed with TFN
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3aye:
Crystal structure of galectin-3 CRD domian complexed with lactose
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-THR:
THREONINE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-NPO:
P-NITROPHENOL

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / Rossmann Fold / a beta-galactose-binding protein / beta-galactosides / cell-surface / nuclear / a -galactose-binding protein

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