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Structure paper

TitleStructural basis of RNA recognition and activation by innate immune receptor RIG-I.
Journal, issue, pagesNature, Vol. 479, Page 423-427, Year 2011
Publish dateOct 2, 2015 (structure data deposition date)
AuthorsJiang, F. / Ramanathan, A. / Miller, M.T. / Tang, G.Q. / Gale, M. / Patel, S.S. / Marcotrigiano, J.
External linksNature / PubMed:21947008
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-5e3h:
Structural Basis for RNA Recognition and Activation of RIG-I
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-BEF:
BERYLLIUM TRIFLUORIDE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/RNA / Adenosine Triphosphatases / Adenosine Triphosphate / DEAD-box RNA Helicases / Enzyme Activation / Fluorometry / Humans / Immunity / Innate / Models / Molecular / Nucleic Acid Conformation / Pliability / Protein Binding / Protein Structure / Tertiary / Proteolysis / RNA / Double-Stranded / RNA-Binding Proteins / Scattering / Small Angle / Structure-Activity Relationship / Substrate Specificity / Trypsin / HYDROLASE / HYDROLASE-RNA complex

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