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TitleCrystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response Element.
Journal, issue, pagesMol Cancer Res, Vol. 9, Page 1493-1499, Year 2011
Publish dateSep 12, 2011 (structure data deposition date)
AuthorsEmamzadah, S. / Tropia, L. / Halazonetis, T.D.
External linksMol Cancer Res / PubMed:21933903
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3ts8:
Crystal structure of a multidomain human p53 tetramer bound to the natural CDKN1A(p21) p53-response element
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsANTITUMOR PROTEIN/DNA / beta sandwich / multidomain / oligomerization / TP53 / p53 / tumor suppressor / tetramer / DNA binding / ANTITUMOR PROTEIN-DNA complex

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